Leukotriene E4

Leukotriene E4

Preferred IUPAC name Leukotriene E4
Systematic name 6-[(2-amino-2-carboxyethyl)sulfanyl]-5-hydroxyicosa-7,9,11,14-tetraenoic acid
Identifiers
CAS number	75715-89-8
PubChem	5280749 (5S,6R,7E,9E,11Z,14Z),() ^Y, 5353718 (7E,9E,11E,14E),() ^Y, 44208907 (7E,9E,11Z,14Z),() ^Y, 53308 (5S,6R),(), 3909 (),() ^Y
ChemSpider	21467210 (5S,7Z,9Z,11E,14Z),() ^Y, 21467208 (5S,7Z,9Z,11Z,14Z),() ^Y, 15170118 (7E,9E,11E,14E),() ^Y, 21237688 (5S,6R),(2R) ^Y, 48147 (5S,6R),() ^Y, 3772 (),() ^Y
KEGG	C05952
MeSH	Leukotriene+E4
ChEBI	CHEBI:15650
Jmol-3D images	Image 1
SMILES CCCCCC=CCC=CC=CC=CC(SCC(N)C(O)=O)C(O)CCCC(O)=O
InChI InChI=1S/C23H37NO5S/c1-2-3-4-5-6-7-8-9-10-11-12-13-16-21(30-18-19(24)23(28)29)20(25)15-14-17-22(26)27/h6-7,9-13,16,19-21,25H,2-5,8,14-15,17-18,24H2,1H3,(H,26,27)(H,28,29) Key: OTZRAYGBFWZKMX-UHFFFAOYSA-N
Properties
Molecular formula	C23H37NO5S
Molar mass	439.61
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Leukotriene E4 is a leukotriene.

Precursor

Precursor

Active

D/J	D₂

E/F	E₂ (Dinoprostone): Enprostil · Sulprostone E₁ (Alprostadil): Misoprostol · Gemeprost F_2α (Dinoprost): Bimatoprost · Carboprost · Latanoprost · Tafluprost · Travoprost · Unoprostone

I	I₂ (Prostacyclin/Epoprostenol): Beraprost · Iloprost · Treprostinil

A₂ · B₂

Precursor	Arachidonic acid 5-hydroperoxide

Initial	A₄ · B₄

SRS-A	C₄ · D₄ · E₄

By function

platelets: induce (TXA₂) inhibit (PGD₂, PGI₂) · leukocytes: induce (TXA₂, LTB₄) inhibit (PGD₂, PGE₂)

fever stimulation: (PGE₂)

labor stimulation: (PGE₂ (Dinoprostone), PGF_2α (Dinoprost))

mt, k, c/g/r/p/y/i, f/h/s/l/o/e, a/u, n, m

k, cgrp/y/i, f/h/s/l/o/e, au, n, m, epon

m(A16/C10),i(k, c/g/r/p/y/i, f/h/s/o/e, a/u, n, m)

biochemical families: prot · nucl · carb (glpr, alco, glys) · lipd (fata/i, phld, strd, gllp, eico) · amac/i · ncbs/i · ttpy/i